Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130088 | 0.76 | IDO1 (0.61) | MEN1KMT2AHRH3IDO1SIGMAR1 | |
| SCHEMBL7449325 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL626848 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL7449055 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL8048487 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL7448881 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL198134 | 0.75 | TSHR (0.52) | TDP1MEN1KMT2AHRH3IDO1 | |
| SCHEMBL18301299 | 0.75 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL22873145 | 0.75 | HTR2A (0.50) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL9021210 | 0.75 | TDP1 (0.45) | TDP1L3MBTL1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020110056-A1 | COMPOUNDS USEFUL IN HIV THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-06-04 | — | — | WO | disclosed |