Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.49 |
| ▸ | ADH1C | P00326 | 1/20 | 0.49 |
| ▸ | ADH1A | P07327 | 1/20 | 0.49 |
| ▸ | ADH7 | P40394 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22456651 | 0.89 | TP53 (0.60) | TP53ALDH1A1USP2HPGDBLM | |
| SCHEMBL5358067 | 0.82 | ALDH1A1 (0.59) | TP53ALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL5358226 | 0.82 | TP53 (0.57) | TP53ALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL5361142 | 0.80 | SMN1; SMN2 (0.65) | TP53ALDH1A1HPGDBLMSMN1; SMN2 | |
| SCHEMBL5358075 | 0.76 | MCHR1 (0.51) | TP53ALDH1A1USP2HPGDTSHR | |
| SCHEMBL3455684 | 0.74 | USP2 (0.50) | TP53ALDH1A1USP2HPGDBLM | |
| SCHEMBL24304646 | 0.74 | ALDH1A1 (0.43) | TP53ALDH1A1USP2HPGDADH1B | |
| SCHEMBL1193938 | 0.74 | NAMPT (0.45) | TP53LMNA | |
| SCHEMBL5373226 | 0.73 | ALDH1A1 (0.52) | TP53ALDH1A1USP2HPGDLMNA | |
| SCHEMBL5354227 | 0.73 | SRC (0.50) | ALDH1A1USP2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020110056-A1 | COMPOUNDS USEFUL IN HIV THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-06-04 | — | — | WO | disclosed |