Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29878722 | 0.85 | PARP15 (0.45) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL22054378 | 0.85 | PARP15 (0.45) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL10268046 | 0.84 | PARP15 (0.44) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL595139 | 0.84 | PARP15 (0.44) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL20476347 | 0.84 | PARP15 (0.47) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL28863087 | 0.84 | PARP15 (0.44) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL23654380 | 0.81 | PARP15 (0.42) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL23030274 | 0.81 | PARP15 (0.42) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL18808792 | 0.81 | PARP15 (0.42) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL596525 | 0.81 | PARP15 (0.44) | PARP15PARP10PARP2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172560-A1 | PROCESS FOR PREPARATION OF CRISABOROLE | GLENMARK LIFE SCIENCES LIMITED (IN) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172560-A1 | PROCESS FOR PREPARATION OF CRISABOROLE | CFB, F13B, C9 | PARP15 1819/4885PARP10 3652/4885PARP2 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.