Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054640 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL22054572 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL20792784 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL25573548 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL17453157 | 0.81 | CPB2 (0.47) | SMN1; SMN2 | |
| SCHEMBL22054642 | 0.81 | CPB2 (0.47) | SMN1; SMN2 | |
| SCHEMBL24860120 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL20801400 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1EPHX2HDAC4HDAC1 | |
| SCHEMBL22054574 | 0.79 | CPB2 (0.45) | SMN1; SMN2 | |
| SCHEMBL24107359 | 0.79 | EPHX1 (0.41) | SMN1; SMN2EPHX1EPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020107078-A1 | DENDRIMER FOR THERAPY AND IMAGING | STARPHARMA PTY LTD (AU) | 2020-06-04 | — | — | WO | disclosed |