Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.57 |
| ▸ | JAK3 | P52333 | 15/20 | 0.57 |
| ▸ | JAK1 | P23458 | 12/20 | 0.56 |
| ▸ | JAK2 | O60674 | 9/20 | 0.53 |
| ▸ | AURKA | O14965 | 4/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054308 | 0.97 | TYK2 (0.59) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL22054315 | 0.91 | TYK2 (0.58) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878972 | 0.91 | TYK2 (0.58) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878915 | 0.89 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL22054316 | 0.89 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23879049 | 0.88 | TYK2 (0.67) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23879047 | 0.88 | TYK2 (0.67) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL22054307 | 0.85 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878979 | 0.85 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878874 | 0.84 | TYK2 (0.60) | TYK2JAK3JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108613-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏豪森药业集团有限公司 | 2020-06-04 | — | — | WO | disclosed |