Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 13/20 | 0.67 |
| ▸ | JAK3 | P52333 | 12/20 | 0.58 |
| ▸ | JAK1 | P23458 | 10/20 | 0.56 |
| ▸ | JAK2 | O60674 | 6/20 | 0.54 |
| ▸ | AURKA | O14965 | 7/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879047 | 1.00 | TYK2 (0.67) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878979 | 0.97 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL22054307 | 0.97 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878915 | 0.92 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL22054316 | 0.92 | TYK2 (0.62) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878793 | 0.89 | TYK2 (0.73) | TYK2JAK3JAK1JAK2 | |
| SCHEMBL23878791 | 0.89 | TYK2 (0.73) | TYK2JAK3JAK1JAK2 | |
| SCHEMBL22055056 | 0.88 | TYK2 (0.57) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878972 | 0.88 | TYK2 (0.58) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL23878914 | 0.88 | TYK2 (0.58) | TYK2JAK3JAK1JAK2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003441-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-115925705-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116003441-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115925705-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| CN-115667228-A | Salt and crystal form of heteroaromatic derivative and preparation method of salt and crystal form | 上海翰森生物医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-111511738-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-01-20 | — | — | CN | disclosed |
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE2, WEE1, RORB | TYK2 105/4885JAK3 88/4885JAK1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.