SCHEMBL220579

SCHEMBL220579

C=C(C)C(=O)N1CCN(C(=O)CC(C)=O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 1/20 0.32
POLB P06746 3/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
EPHX2 P34913 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429460 0.85 ALDH1A1 (0.44) ALDH1A1KMT2AKDM4ETDP1HSD17B10
SCHEMBL269621 0.82 TDP1 (0.42) ALDH1A1KMT2AKDM4ETDP1MEN1
SCHEMBL236549 0.82
SCHEMBL2418391 0.79 TDP1 (0.52) ALDH1A1KMT2AKDM4ETDP1HSD17B10
SCHEMBL6669128 0.79 ATM (0.44) ALDH1A1KMT2AKDM4ETDP1HSD17B10
SCHEMBL13756057 0.77 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4ETDP1HSD17B10
SCHEMBL26510144 0.77 BLM (0.47) ALDH1A1KMT2AKDM4ETDP1HSD17B10
SCHEMBL2414622 0.77 TDP1 (0.56) KMT2AKDM4ETDP1HTTSMN1; SMN2
SCHEMBL6580359 0.77 ALDH1A1 (0.36) ALDH1A1POLBHTTSMN1; SMN2TSHR
SCHEMBL2416856 0.76 ATM (0.46) ALDH1A1KMT2AKDM4ETDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066376-A Crosslinked Acrylamide Type Gel Medium EASTMAN KODAK COMPANY (US) 1991-11-19 US claimed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
US-4421915-A Polymerizable ethylenically unsaturated amide compounds EASTMAN KODAK COMPANY (US) 1983-12-20 US claimed
EP-0013147-B1 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-10-26 EP claimed
US-4247673-A COLOR COUPLERS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US claimed
US-4215195-A CROSSLINKABLE, POLYMERIC COLOR COUPLERS, GELATIN EXTENDERS, BINDERS EASTMAN KODAK COMPANY (US) 1980-07-29 US claimed
EP-0013147-A2 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-09 EP claimed
EP-1539832-B2 SELF-CROSSLINKABLE WATERBORNE COATING COMPOSITION VALSPAR SOURCING INC (US) 2014-08-06 EP disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
US-7829631-B2 Self-crosslinkable waterborne coating composition VALSPAR SOURCING, INC. (US) 2010-11-09 US disclosed
US-7560519-B2 Dual-stage wafer applied underfills LORD CORPORATION (US) 2009-07-14 US disclosed
EP-1539832-B1 SELF-CROSSLINKABLE WATERBORNE COATING COMPOSITION VALSPAR SOURCING INC (US) 2009-04-01 EP disclosed
EP-2001963-A1 INKJET INK SET E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP disclosed
US-4438278-A CROSSLINKABLE MONOMERS EASTMAN KODAK COMPANY (US) 1984-03-20 US disclosed
US-4421915-A Polymerizable ethylenically unsaturated amide compounds EASTMAN KODAK COMPANY (US) 1983-12-20 US disclosed
EP-0013147-B1 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-10-26 EP disclosed
US-4346231-A Polymerizable ethylenically unsaturated amide compounds PONTICELLO IGNAZIO S 1982-08-24 US disclosed
US-4247673-A COLOR COUPLERS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4215195-A CROSSLINKABLE, POLYMERIC COLOR COUPLERS, GELATIN EXTENDERS, BINDERS EASTMAN KODAK COMPANY (US) 1980-07-29 US disclosed
EP-0013147-A2 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-09 EP disclosed