Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954788 | 0.74 | TNKS (0.51) | TNKSPARP1TNKS2 | |
| SCHEMBL21989251 | 0.73 | — | — | |
| SCHEMBL20955731 | 0.65 | TNKS (0.43) | TNKSPARP1TNKS2 | |
| SCHEMBL20954967 | 0.62 | POLB (0.40) | TNKSPARP1TNKS2 | |
| SCHEMBL9955521 | 0.61 | SMN1; SMN2 (0.42) | TNKSPARP1TNKS2 | |
| SCHEMBL16710701 | 0.57 | CYP2C19 (0.39) | HRH4 | |
| SCHEMBL1339261 | 0.57 | — | — | |
| SCHEMBL3542184 | 0.56 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL3425801 | 0.55 | ADORA3 (0.36) | — | |
| SCHEMBL3390495 | 0.55 | KMT2A (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414429-B2 | Compound or pharmaceutically acceptable salt thereof | RIKEN (JP) | 2022-08-16 | — | — | US | disclosed |
| US-20200172554-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | RIKEN (JP) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414429-B2 | Compound or pharmaceutically acceptable salt thereof | DPP8, DPP7, AZI2 | HRH4 2602/4885TNKS 3604/4885PARP1 1705/4885 |
| US-20200172554-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | DPP8, DPP7, AZI2 | HRH4 2495/4885TNKS 3690/4885PARP1 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.