SCHEMBL22058409

SCHEMBL22058409

c1ccc(-c2ccc3c(c2)Oc2ccccc2N3c2cccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
PKM P14618 2/20 0.38
FAAH O00519 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
MGLL Q99685 1/20 0.38
HPSE Q9Y251 2/20 0.37
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GRM5 P41594 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17206603 0.99 ALDH1A1 (0.39) ALDH1A1PKMFAAHHSP90AA1HTT
SCHEMBL17206608 0.96 ADORA2A (0.34) ALDH1A1PKMFAAHHSP90AA1HTT
SCHEMBL13833098 0.95 ADORA2A (0.35) ALDH1A1PKMHPSEADORA2AADORA1
SCHEMBL16271064 0.91 ALDH1A1 (0.38) ALDH1A1PKMFAAHHSP90AA1HTT
SCHEMBL13833010 0.91 ALDH1A1 (0.38) ALDH1A1PKMFAAHHSP90AA1HTT
SCHEMBL17278519 0.90 ADORA2A (0.36) ALDH1A1PKMFAAHHTTMGLL
SCHEMBL17278490 0.90 PDE6D (0.39) ALDH1A1FAAHMGLLADORA2AADORA1
SCHEMBL17278522 0.90 PDE6D (0.39) ALDH1A1FAAHMGLLADORA2AADORA1
SCHEMBL17278503 0.90 ADORA2A (0.36) ALDH1A1PKMHTTADORA2AADORA1
SCHEMBL20230604 0.89 ADORA2A (0.37) ALDH1A1PKMADORA2AADORA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227644-A1 ORGANIC LIGHT-EMITTING DIODE OPERABLE AT LOW VOLTAGE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2020-07-16 US disclosed
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 EP disclosed