Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22058558 | 0.96 | HCRTR1 (0.37) | HCRTR1TTRAHRMAPTKMT2A | |
| SCHEMBL24097623 | 0.94 | ALOX5 (0.44) | HCRTR1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL21707353 | 0.92 | HCRTR1 (0.35) | HCRTR1AHRMAPTKMT2AMEN1 | |
| SCHEMBL27069023 | 0.91 | MEN1 (0.34) | HCRTR1TTRKMT2AMEN1ALDH1A1 | |
| SCHEMBL24293796 | 0.90 | TTR (0.33) | HCRTR1TTRAHRMAPTKMT2A | |
| SCHEMBL27069024 | 0.90 | HCRTR1 (0.33) | HCRTR1TTRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27069385 | 0.90 | HCRTR1 (0.33) | HCRTR1TTRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27069381 | 0.90 | HCRTR1 (0.33) | HCRTR1TTRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23935959 | 0.90 | AHR (0.33) | HCRTR1TTRAHRMAPTKMT2A | |
| SCHEMBL20465211 | 0.90 | CHEK2 (0.39) | TTRAHRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230059210-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2020109269-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |