Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001535 | 0.90 | MEN1 (0.58) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL22059567 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL22059590 | 0.80 | MEN1 (0.70) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL12651747 | 0.74 | CYP19A1 (0.71) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL304258 | 0.74 | MAOB (0.86) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29363687 | 0.74 | MAOB (0.86) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2911015 | 0.74 | MAOB (0.80) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL51872 | 0.73 | MEN1 (0.82) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2028924 | 0.73 | MAOB (0.76) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL42693 | 0.72 | ALDH1A1 (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660008-A1 | COUMARIN OXIME ESTER COMPOUND AND PREPARATION AND USE THEREOF | Hubei Gurun Technology Co., Ltd (CN) | 2020-06-03 | — | — | EP | disclosed |