Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12131750 | 0.87 | ERCC1 (0.70) | ERCC1ERCC4MAPTGAAMEN1 | |
| SCHEMBL24558042 | 0.82 | ERCC1 (0.64) | ERCC1ERCC4MAPTALDH1A1MEN1 | |
| SCHEMBL22060051 | 0.81 | PTPRZ1 (0.64) | ERCC1ERCC4EPHX2NR1H4MAPT | |
| SCHEMBL12757443 | 0.80 | KMT2A (0.63) | ERCC1ERCC4NPC1RAB9AALDH1A1 | |
| SCHEMBL18887748 | 0.80 | ERCC1 (0.67) | ERCC1ERCC4MAPTMEN1KMT2A | |
| SCHEMBL29260504 | 0.80 | MAPT (0.59) | EPHX2NR1H4NPC1MAPTRAB9A | |
| SCHEMBL22060015 | 0.80 | ERCC1 (0.62) | ERCC1ERCC4EPHX2MAPTMEN1 | |
| SCHEMBL12134066 | 0.80 | ERCC1 (0.62) | ERCC1ERCC4MAPTRAB9AALDH1A1 | |
| SCHEMBL6017524 | 0.80 | KMT2A (0.59) | EPHX2NR1H4NPC1MAPTRAB9A | |
| SCHEMBL25657185 | 0.79 | EPHX2 (0.48) | EPHX2NR1H4NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN (DE) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | NR1H4, NR1H3, NR1H2 | ERCC1 2685/4885ERCC4 1558/4885EPHX2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.