Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20994733 | 0.91 | — | — | |
| SCHEMBL20536873 | 0.91 | — | — | |
| SCHEMBL20536871 | 0.91 | — | — | |
| SCHEMBL20994229 | 0.89 | PTGIR (0.39) | PTGER4ALDH1A1PTGIRLMNAHPGD | |
| SCHEMBL20218734 | 0.81 | MEN1 (0.32) | ALDH1A1PTGIRLMNAHPGDTSHR | |
| SCHEMBL20536595 | 0.81 | MEN1 (0.32) | ALDH1A1PTGIRLMNAHPGDTSHR | |
| SCHEMBL20536596 | 0.81 | MEN1 (0.32) | ALDH1A1PTGIRLMNAHPGDTSHR | |
| SCHEMBL20536955 | 0.79 | — | — | |
| SCHEMBL20536953 | 0.79 | — | — | |
| SCHEMBL14732832 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483168-B1 | PROCESSES FOR PREPARING CYCLOPENTA[B]NAPHTHALENOL DERIVATIVES AND INTERMEDIATES THEREOF | CHIROGATE INT INC (TW) | 2020-06-03 | — | — | EP | disclosed |