Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20536596 | 0.92 | MEN1 (0.32) | PTGIRMEN1KMT2AMAPK1TP53 | |
| SCHEMBL20536595 | 0.92 | MEN1 (0.32) | PTGIRMEN1KMT2AMAPK1TP53 | |
| SCHEMBL20218734 | 0.92 | MEN1 (0.32) | PTGIRMEN1KMT2AMAPK1TP53 | |
| SCHEMBL22060610 | 0.89 | PTGER4 (0.36) | PTGIRPTGER4MAPK1TSHRHIF1A | |
| SCHEMBL20218870 | 0.82 | CYP4F2 (0.32) | MEN1KMT2AMAPK1TP53CYP1A2 | |
| SCHEMBL14715869 | 0.82 | CYP4F2 (0.32) | MEN1KMT2AMAPK1TP53CYP1A2 | |
| SCHEMBL14715871 | 0.82 | CYP4F2 (0.32) | MEN1KMT2AMAPK1TP53CYP1A2 | |
| SCHEMBL14715868 | 0.82 | CYP4F2 (0.32) | MEN1KMT2AMAPK1TP53CYP1A2 | |
| SCHEMBL20536871 | 0.81 | — | — | |
| SCHEMBL20994733 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483168-A1 | PROCESSES FOR PREPARING CYCLOPENTA[B]NAPHTHALENOL DERIVATIVES AND INTERMEDIATES THEREOF | Chirogate International Inc. (TW) | 2019-05-15 | — | — | EP | disclosed |