Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22060752 | 0.76 | MAPT (0.39) | TTRINSRIGF1RALDH1A1MAPT | |
| SCHEMBL22061374 | 0.75 | MAPT (0.40) | TTRINSRIGF1RALDH1A1MAPT | |
| SCHEMBL22061549 | 0.72 | MKNK1 (0.62) | MKNK1 | |
| SCHEMBL22061566 | 0.71 | MKNK1 (0.62) | MKNK1 | |
| SCHEMBL22061421 | 0.67 | MKNK1 (0.30) | MKNK2MKNK1 | |
| SCHEMBL22061375 | 0.65 | PDE7A (0.36) | TTRINSRIGF1RALDH1A1MAPT | |
| SCHEMBL3296747 | 0.65 | ALDH1A1 (0.42) | TTRINSRIGF1RALDH1A1 | |
| SCHEMBL17362927 | 0.64 | MKNK1 (0.55) | MKNK2MKNK1 | |
| SCHEMBL22061372 | 0.64 | PDE7A (0.38) | TTRINSRIGF1RALDH1A1MAPT | |
| SCHEMBL17362618 | 0.63 | MKNK1 (0.57) | MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253397-B | MNK inhibitors | 上海迪诺医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |