SCHEMBL22062166

SCHEMBL22062166

CC(C)C(=O)c1cccc(/N=N/Nc2cccc(C(=O)C(C)C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.46
RAB9A P51151 8/20 0.46
MAPT P10636 7/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
CYP1A1 P04798 2/20 0.41
CYP1B1 Q16678 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
DBH P09172 1/20 0.38
RECQL P46063 1/20 0.38
POLB P06746 1/20 0.37
HSP90AA1 P07900 1/20 0.37
VCP P55072 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22062138 0.84 CYP1A1 (0.55) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062006 0.82 RAB9A (0.59) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062003 0.81 HDAC8 (0.49) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL11880967 0.81 MEN1 (0.48) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062142 0.81 MEN1 (0.48) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062002 0.80 NPC1 (0.46) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062005 0.78 KMT2A (0.55) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL13500591 0.75 GAA (0.47) SMN1; SMN2KMT2AALDH1A1GAAKDM4E
SCHEMBL10332163 0.75 KDM4E (0.47) NPC1RAB9AMAPTSMN1; SMN2MEN1
SCHEMBL22062001 0.74 RAB9A (0.72) NPC1RAB9AMAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10678156-B2 Pigment dispersion, method for manufacturing toner, aqueous ink, and triazo compound CANON KABUSHIKI KAISHA (JP) 2020-06-09 US disclosed