⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682705 | 0.86 | — | — | |
| SCHEMBL94566 | 0.78 | — | — | |
| SCHEMBL3068716 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL3078846 | 0.77 | TSHR (0.45) | — | |
| SCHEMBL2205401 | 0.74 | — | — | |
| SCHEMBL170631 | 0.72 | — | — | |
| SCHEMBL5067235 | 0.72 | TSHR (0.48) | — | |
| SCHEMBL21541203 | 0.72 | — | — | |
| SCHEMBL125606 | 0.71 | KMT2A (0.48) | — | |
| SCHEMBL984694 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210627-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2022-12-21 | — | — | EP | disclosed |
| EP-3558391-B1 | IMMUNOCONJUGATES TARGETING ADAM9 AND METHODS OF USE THEREOF | IMMUNOGEN INC (US) | 2022-02-02 | — | — | EP | disclosed |
| EP-3842459-A1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | ImmunoGen, Inc. (US) | 2021-06-30 | — | — | EP | disclosed |
| EP-3313884-B9 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN INC (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-3313884-B1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3189056-B1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-06-10 | — | — | EP | disclosed |