SCHEMBL22065263

SCHEMBL22065263

O[n+]1onc2cc(Cl)c(Br)cc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.35
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2588191 0.79 GRIA2 (0.46) AHR
SCHEMBL2594620 0.66 AHR (0.44) AHRCSNK2A1
SCHEMBL3307757 0.63 AHR (0.41) AHRCSNK2A1
SCHEMBL1750595 0.62 GRIA2 (0.51)
SCHEMBL8686838 0.62 GRIA2 (0.51)
SCHEMBL3850787 0.60 AHR (0.58) AHRCSNK2A1
SCHEMBL21703753 0.60 TRPA1 (0.35)
SCHEMBL17031439 0.58 CSNK2A1 (0.34) AHRCSNK2A1
SCHEMBL22064759 0.58
SCHEMBL11282194 0.58 AHR (0.55) AHRCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970186-B1 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC) PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2020-06-10 EP disclosed