Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | IDH1 | O75874 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470036 | 0.92 | KMT2A (0.67) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL22065300 | 0.88 | MEN1 (0.62) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL22025448 | 0.87 | IDH1 (0.61) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL22024988 | 0.87 | MAPT (0.62) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL22025522 | 0.86 | MAPT (0.60) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL22025430 | 0.86 | MEN1 (0.59) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL17131157 | 0.85 | MAPK14 (0.72) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL19073209 | 0.85 | BRAF (0.73) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL17079632 | 0.84 | DDX3X (0.73) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL6371123 | 0.83 | TRPV1 (0.67) | MEN1KMT2AMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663293-A1 | SUBSTITUTED PENTA- AND HEXA-HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, DRUG COMBINATION AND USE THEREOF | Xiamen University (CN) | 2020-06-10 | — | — | EP | disclosed |