Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.63 |
| ▸ | ABL1 | P00519 | 6/20 | 0.47 |
| ▸ | BCR | P11274 | 6/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22024706 | 0.87 | PIKFYVE (0.78) | PIKFYVEABL1BCRPDGFRBSRC | |
| SCHEMBL22024549 | 0.80 | PIKFYVE (0.59) | PIKFYVEABL1BCRPDGFRBPDGFRA | |
| SCHEMBL22025456 | 0.78 | PIKFYVE (0.75) | PIKFYVEABL1BCRPDGFRBPDGFRA | |
| SCHEMBL22025126 | 0.78 | PIKFYVE (0.74) | PIKFYVEABL1BCRPDGFRBPDGFRA | |
| SCHEMBL22024552 | 0.78 | PIKFYVE (0.74) | PIKFYVEABL1BCRPDGFRBSRC | |
| SCHEMBL22024870 | 0.77 | PIKFYVE (1.00) | PIKFYVEABL1BCRPDGFRBSRC | |
| SCHEMBL22024551 | 0.77 | PIKFYVE (0.88) | PIKFYVEABL1BCRPDGFRBSRC | |
| SCHEMBL30675086 | 0.77 | PIKFYVE (1.00) | PIKFYVEABL1BCRPDGFRBSRC | |
| SCHEMBL22024994 | 0.77 | PIKFYVE (0.72) | PIKFYVEABL1BCRPDGFRBPDGFRA | |
| SCHEMBL22025012 | 0.76 | PIKFYVE (0.70) | PIKFYVEABL1BCRPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663293-A1 | SUBSTITUTED PENTA- AND HEXA-HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, DRUG COMBINATION AND USE THEREOF | Xiamen University (CN) | 2020-06-10 | — | — | EP | disclosed |