Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 1.00 |
| ▸ | BRAF | P15056 | 8/20 | 0.64 |
| ▸ | CSF1R | P07333 | 4/20 | 0.64 |
| ▸ | TEK | Q02763 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 4/20 | 0.56 |
| ▸ | BCR | P11274 | 3/20 | 0.56 |
| ▸ | ESYT2 | A0FGR8 | 2/20 | 0.55 |
| ▸ | NBAS | A2RRP1 | 2/20 | 0.55 |
| ▸ | CNOT1 | A5YKK6 | 2/20 | 0.55 |
| ▸ | TBKBP1 | A7MCY6 | 2/20 | 0.55 |
| ▸ | AGPS | O00116 | 2/20 | 0.55 |
| ▸ | MYO1F | O00160 | 2/20 | 0.55 |
| ▸ | SNAP23 | O00161 | 2/20 | 0.55 |
| ▸ | AP3B1 | O00203 | 2/20 | 0.55 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.55 |
| ▸ | PGRMC1 | O00264 | 2/20 | 0.55 |
| ▸ | CLIC1 | O00299 | 2/20 | 0.55 |
| ▸ | CDC7 | O00311 | 2/20 | 0.55 |
| ▸ | IPO5 | O00410 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22024870 | 1.00 | PIKFYVE (1.00) | PIKFYVEBRAFCSF1RTEKABL1 | |
| SCHEMBL22024551 | 0.94 | PIKFYVE (0.88) | PIKFYVEBRAFCSF1RABL1BCR | |
| SCHEMBL22024864 | 0.92 | PIKFYVE (0.85) | PIKFYVEBRAFCSF1RTEKPDGFRB | |
| SCHEMBL22024534 | 0.92 | PIKFYVE (0.85) | PIKFYVEBRAFCSF1RTEKLCK | |
| SCHEMBL22025017 | 0.90 | PIKFYVE (0.82) | PIKFYVEBRAFCSF1RABL1BCR | |
| SCHEMBL22024537 | 0.90 | PIKFYVE (0.82) | PIKFYVEBRAFCSF1RTEKPDGFRB | |
| SCHEMBL22024533 | 0.90 | PIKFYVE (0.81) | PIKFYVEBRAFCSF1RTEKLMNA | |
| SCHEMBL22024690 | 0.90 | PIKFYVE (0.81) | PIKFYVEBRAFCSF1RTEKABL1 | |
| SCHEMBL22024700 | 0.90 | PIKFYVE (0.81) | PIKFYVEBRAFCSF1RTEKABL1 | |
| SCHEMBL22024863 | 0.89 | PIKFYVE (0.80) | PIKFYVEBRAFCSF1RTEKPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789642-A | Tri-aromatic heterocyclic piperazine compound for inducing tumor cell to generate meta death and application thereof | 华东师范大学 | 2023-09-22 | — | — | CN | disclosed |