SCHEMBL22067387

SCHEMBL22067387

N#Cc1ccc2c(c1)c1ccccc1n2-c1cccc(-n2c3ccc(C#N)cc3c3cc(-c4ccc5c(c4)C4(c6ccccc6O5)c5cccnc5-c5ncccc54)ccc32)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 1/20 0.32
▸ CRBN Q96SW2 1/20 0.32
▸ RPS6KB1 P23443 1/20 0.32
▸ GRM5 P41594 5/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ TDO2 P48775 2/20 0.31
▸ PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22067365 1.00 DDB1 (0.32) DDB1CRBNRPS6KB1GRM5KDM4E
SCHEMBL22067417 0.97 DDB1 (0.32) DDB1CRBNRPS6KB1GRM5KDM4E
SCHEMBL22067423 0.97 DDB1 (0.32) DDB1CRBNRPS6KB1GRM5KDM4E
SCHEMBL22067440 0.96 DDB1 (0.31) DDB1CRBNRPS6KB1
SCHEMBL22067443 0.96 DDB1 (0.31) DDB1CRBNRPS6KB1
SCHEMBL22065661 0.95 PTGER4 (0.30) GRM5PTGER4
SCHEMBL22065683 0.95 PTGER4 (0.30) GRM5PTGER4
SCHEMBL22067378 0.95 DDB1 (0.33) DDB1CRBNRPS6KB1TDO2PTGER4
SCHEMBL22067386 0.95 DDB1 (0.33) DDB1CRBNRPS6KB1TDO2PTGER4
SCHEMBL22066705 0.94 DDB1 (0.32) DDB1CRBNTDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200185622-A1 Novel Compound, and Organic Light Emitting Device and Organic Light Emitting Display Device Including the Same DONGJIN SEMICHEM CO., LTD. (KR) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200185622-A1 Novel Compound, and Organic Light Emitting Device and Organic Light Emitting Display Device Including the Same ALDH1A2, DDT, TYR DDB1 387/4885CRBN 1937/4885RPS6KB1 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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