Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 16/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22247002 | 0.85 | RORC (0.51) | KDM4EMEN1KMT2ASMN1; SMN2RXFP1 | |
| SCHEMBL20903865 | 0.85 | RORC (0.53) | RORC | |
| SCHEMBL22068360 | 0.82 | RORC (0.60) | RORC | |
| SCHEMBL22069509 | 0.81 | RORC (0.52) | RORC | |
| SCHEMBL22069256 | 0.79 | RORC (0.50) | RORC | |
| SCHEMBL1175397 | 0.78 | KDM4E (0.54) | KDM4EMEN1KMT2ASMN1; SMN2RXFP1 | |
| SCHEMBL20903832 | 0.74 | RORC (0.49) | RORC | |
| SCHEMBL18647650 | 0.72 | RORC (0.57) | RORC | |
| SCHEMBL20903773 | 0.71 | RORC (0.52) | RORC | |
| SCHEMBL23223365 | 0.71 | RORC (0.61) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663299-A1 | BICYCLIC COMPOUND ACTING AS ROR INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-10 | — | — | EP | disclosed |