⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327027 | 0.76 | — | — | |
| SCHEMBL9423011 | 0.75 | — | — | |
| SCHEMBL1753033 | 0.74 | — | — | |
| SCHEMBL11425647 | 0.74 | ALDH1A1 (0.50) | — | |
| SCHEMBL4779916 | 0.73 | — | — | |
| SCHEMBL15649073 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL10925596 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL19318891 | 0.71 | ALDH1A1 (0.53) | — | |
| SCHEMBL80284 | 0.71 | — | — | |
| SCHEMBL141446 | 0.71 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824438-A | Novel synthesis method of polyimide | 湘潭大学 | 2021-05-21 | — | — | CN | claimed |
| WO-2022126947-A1 | ENVIRONMENTALLY FRIENDLY PREPARATION METHOD FOR SUBSTITUTED ISONITRILE COMPOUND | 新发药业有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-112824438-B | Synthetic method of polyimide | 湘潭大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-112824438-A | Novel synthesis method of polyimide | 湘潭大学 | 2021-05-21 | — | — | CN | disclosed |
| US-9163007-B2 | 5-substituted indazoles as kinase inhibitors | ABBVIE INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140343066-A1 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-11-20 | — | — | US | disclosed |
| US-8648069-B2 | 5-substituted indazoles as kinase inhibitors | ABBVIE INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-7981890-B2 | Phthalazinone derivatives | ASTRAZENECA AB (SE) | 2011-07-19 | — | — | US | disclosed |
| EP-2188278-A1 | PHTHALAZINONE DERIVATIVES | AstraZeneca AB (SE) | 2010-05-26 | — | — | EP | disclosed |
| EP-2167491-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | Abbott Laboratories (US) | 2010-03-31 | — | — | EP | disclosed |
| US-4239528-A | Plant growth regulating compositions and methods using alpha-isocyanocarboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4206216-A | Antihypertensive N-heterocyclicalanines | MERCK & CO., INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009710-A1 | Alpha-isocyano-cyclopropyl amides, process for their preparation, and their application as plant growth regulants | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |
| US-4170654-A | Antihypertensive compositions containing N-heterocyclicalanines and α- | MERCK & CO., INC. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4160835-A | Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid | MERCK & CO., INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4156734-A | Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid | MERCK & CO., INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4153715-A | Indolyl amino acids useful as antihypertensive agents | MERCK & CO., INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4098600-A | POSTEMERGENCE HERBICIDES, GROWTH REGULATORS FOR CORN | MONSANTO COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4065572-A | Amino acids and esters thereof useful as antihypertensive agents | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4018757-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-04-19 | — | — | US | disclosed |