Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 5/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213493 | 0.92 | VNN1 (0.34) | VNN1ELANEDDR2 | |
| SCHEMBL2206917 | 0.85 | VNN1 (0.34) | VNN1GPBAR1ELANE | |
| SCHEMBL2211768 | 0.85 | VNN1 (0.34) | VNN1GPBAR1ELANE | |
| SCHEMBL14174391 | 0.84 | VNN1 (0.33) | VNN1GPBAR1ELANEDDR2 | |
| SCHEMBL2211998 | 0.84 | KDM4E (0.38) | VNN1ELANE | |
| SCHEMBL2213498 | 0.80 | VNN1 (0.34) | VNN1DDR2 | |
| SCHEMBL2210254 | 0.77 | KDM4E (0.35) | VNN1ELANEDDR2 | |
| SCHEMBL2210261 | 0.77 | KDM4E (0.35) | VNN1ELANEDDR2 | |
| SCHEMBL2212537 | 0.76 | VNN1 (0.33) | VNN1GPBAR1DDR2 | |
| SCHEMBL2212531 | 0.76 | VNN1 (0.33) | VNN1GPBAR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099769-B1 | 6-OXO.-1, 6-DIHYDROPYRIMIDIN-2-YLS IN THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-07-27 | — | — | EP | disclosed |