Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.49 |
| ▸ | ATF1 | P18846 | 7/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22102821 | 0.83 | XPO1 (0.44) | XPO1ATF1NFKB1MAPTMEN1 | |
| SCHEMBL30751960 | 0.81 | XPO1 (0.55) | XPO1ATF1NFKB1MAPTKMT2A | |
| SCHEMBL28830749 | 0.81 | XPO1 (0.55) | XPO1ATF1NFKB1MAPTKMT2A | |
| SCHEMBL22098582 | 0.79 | XPO1 (0.47) | XPO1ATF1NFKB1 | |
| SCHEMBL20808527 | 0.77 | XPO1 (0.60) | XPO1ATF1NFKB1MAPTMEN1 | |
| SCHEMBL22653505 | 0.75 | LMNA (0.37) | MAPTMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL22098611 | 0.75 | XPO1 (0.49) | XPO1ATF1NFKB1MAPTGAA | |
| SCHEMBL474055 | 0.74 | KDM4E (0.57) | XPO1ATF1NFKB1MAPTKDM4E | |
| SCHEMBL1267198 | 0.74 | XPO1 (0.56) | XPO1ATF1NFKB1KMT2AGAA | |
| SCHEMBL21645062 | 0.74 | XPO1 (0.56) | XPO1ATF1NFKB1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120284-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020120284-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-18 | — | — | WO | disclosed |
| EP-3666759-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer Aktiengesellschaft (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666759-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer Aktiengesellschaft (DE) | 2020-06-17 | — | — | EP | disclosed |