SCHEMBL22069732

SCHEMBL22069732

N#CCCn1nnnc1CO

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 3/20 0.51
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
CYP1A2 P05177 2/20 0.37
GHSR Q92847 2/20 0.32
ALDH1A1 P00352 3/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13344348 0.81 NAALAD2 (0.48) NAALAD2GLATSHRCYP1A2GHSR
SCHEMBL7344053 0.79 NAALAD2 (0.52) NAALAD2GLATSHRCYP1A2GHSR
Hydrochloric Acid SCHEMBL15253870 0.74 NAALAD2 (0.45) NAALAD2GLATSHRGHSRALDH1A1
SCHEMBL10673194 0.73 GLA (0.42) NAALAD2GLATSHRCYP1A2GHSR
SCHEMBL15254266 0.72 NAALAD2 (0.49) NAALAD2GLATSHRGHSRALDH1A1
SCHEMBL8923785 0.71 NAALAD2 (0.49) NAALAD2GLATSHRCYP1A2GHSR
Hydrochloric Acid SCHEMBL21494705 0.71 NAALAD2 (0.67) NAALAD2GHSR
Hydrochloric Acid SCHEMBL21494707 0.71 NAALAD2 (0.67) NAALAD2GHSR
SCHEMBL15254268 0.71 NAALAD2 (0.57) NAALAD2GLATSHRGHSRGAA
SCHEMBL4134263 0.70 NAALAD2 (0.47) NAALAD2GLATSHRGHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666769-A1 NOVEL CASPASE INHIBITORS RIJKSUNIVERSITEIT GRONINGEN (NL) 2020-06-17 EP disclosed