Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344348 | 0.79 | NAALAD2 (0.48) | NAALAD2GLATSHRCYP1A2GHSR | |
| SCHEMBL22069732 | 0.79 | NAALAD2 (0.51) | NAALAD2GLATSHRCYP1A2GHSR | |
| Hydrochloric Acid SCHEMBL21494707 | 0.74 | NAALAD2 (0.67) | NAALAD2GHSR | |
| Hydrochloric Acid SCHEMBL21494705 | 0.74 | NAALAD2 (0.67) | NAALAD2GHSR | |
| Hydrochloric Acid SCHEMBL28509376 | 0.72 | NAALAD2 (0.61) | NAALAD2GHSR | |
| Chloromethane SCHEMBL29231841 | 0.72 | NAALAD2 (0.64) | NAALAD2GHSR | |
| SCHEMBL4033007 | 0.72 | ALDH1A1 (0.42) | NAALAD2TSHRCYP1A2 | |
| SCHEMBL28504133 | 0.72 | NAALAD2 (0.60) | NAALAD2GHSR | |
| SCHEMBL21515089 | 0.72 | NAALAD2 (0.60) | NAALAD2GHSR | |
| Hydrochloric Acid SCHEMBL15253870 | 0.71 | NAALAD2 (0.45) | NAALAD2GLATSHRGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |