Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069794 | 0.98 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5970014 | 0.71 | MAPT (0.61) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7699680 | 0.68 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL22069819 | 0.67 | HPGD (0.46) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL23229637 | 0.64 | MAPT (0.61) | ALDH1A1MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL8339210 | 0.64 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5970126 | 0.64 | MAPT (0.96) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL23229431 | 0.62 | MAPT (1.00) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL24415299 | 0.58 | MAPT (0.93) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3083745 | 0.58 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666757-A1 | PROCESS FOR PREPARING A PIPERIDIN-4-ONE | Karl-Franzens-Universität Graz (AT) | 2020-06-17 | — | — | EP | disclosed |