Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071748 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22072071 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22072307 | 0.72 | MEN1 (0.47) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL22072302 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22072092 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22072167 | 0.69 | KDM4E (0.37) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22072146 | 0.68 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22071732 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL14399199 | 0.65 | SMN1; SMN2 (0.58) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL22300771 | 0.65 | MEN1 (0.60) | KDM4EALDH1A1HPGDGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117974-A1 | COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS | AVEDRO, INC. (US) | 2020-06-11 | — | — | WO | disclosed |