⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862831 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL5013430 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL16313108 | 0.69 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6243425 | 0.68 | KDM4E (0.39) | — | |
| SCHEMBL5959974 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL2926049 | 0.67 | — | — | |
| SCHEMBL2076528 | 0.67 | — | — | |
| SCHEMBL19267416 | 0.67 | — | — | |
| SCHEMBL17001553 | 0.67 | — | — | |
| SCHEMBL3024904 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003627-B2 | Urokinase inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2011-08-23 | — | — | US | disclosed |
| US-7981875-B2 | Treating pancreatic cancer by administering cardenolide uscharin extracted from Calotropis procera plants | UNIBIOSCREEN S.A. (BE) | 2011-07-19 | — | — | US | disclosed |
| WO-2009033505-A1 | HELLEBRIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2009-03-19 | — | — | WO | disclosed |
| US-20080312191-A1 | Novel Urokinase Inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2008-12-18 | — | — | US | disclosed |
| US-20080261935-A1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | UNIBIOSCREEN S.A. (BE) | 2008-10-23 | — | — | US | disclosed |
| EP-1940856-A1 | NOVEL UROKINASE INHIBITORS | Universiteit Antwerpen (BE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1709063-B1 | GLYCOSYLATED STEROID DERIVATIVES WITH ANTI-MIGRATORY ACTIVITY | UNIBIOSCREEN SA (BE) | 2008-01-23 | — | — | EP | disclosed |
| US-7320971-B2 | 2″ oxo-voruscharin and derivatives thereof | UNIBIOSCREEN S.A. (BE) | 2008-01-22 | — | — | US | disclosed |
| US-20070123473-A1 | Glycosylated steroid derivatives with anti-migratory activity | UNIBIOSCREEN S.A. (BE) | 2007-05-31 | — | — | US | disclosed |
| WO-2007045496-A1 | NOVEL UROKINASE INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2007-04-26 | — | — | WO | disclosed |
| EP-1551850-A1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | Unibioscreen S.A. (BE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2005058934-A2 | GLYCOSYLATED STEROID DERIVATIVES WITH ANTI-MIGRATORY ACTIVITY | UNIBIOSCREEN S.A. (BE) | 2005-06-30 | — | — | WO | disclosed |
| US-20050119338-A1 | Combination of cytochome p450 dependent protease inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-02 | — | — | US | disclosed |
| EP-1458447-A2 | COMBINATION OF CYTOCHOME P 450 DEPENDENT PROTEASE INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004055039-A1 | STEROID COMPOUNDS WITH ANTI-TUMOR ACTIVITY | UNIBIOSCREEN S.A. (BE) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004033465-A1 | 2' OXO-VORUSCHARIN AND DERIVATIVES THEREOF | UNIBIOSCREEN S.A. (BE) | 2004-04-22 | — | — | WO | disclosed |
| EP-1408043-A1 | 2''oxo-voruscharin and analogues thereof | Unibioscreen S.A. (BE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003049746-A2 | COMBINATION OF CYTOCHOME P450 DEPENDENT PROTEASE INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2003-06-19 | — | — | WO | disclosed |