SCHEMBL2207404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2210452	0.80	PDE7A (0.37)	KDRDHFRCYP1A2DYRK1AMAPK1
	SCHEMBL4555081	0.76	KDR (0.45)	KDRPDGFRATDP1METALDH1A1
	SCHEMBL2209181	0.76	KDR (0.41)	KDRPDGFRAMETCYP3A4LMNA
	SCHEMBL5050795	0.76	PDGFRA (0.61)	KDRPDGFRAMET
	SCHEMBL2206780	0.76	FGFR2 (0.43)	KDRPDGFRANOS3NOS1NOS2
	SCHEMBL16432308	0.75	NOS3 (0.46)	NOS3NOS1NOS2CYP1A2DYRK1A
	SCHEMBL2206890	0.75	KDR (0.41)	KDRPDGFRAMETLMNAMEN1
	SCHEMBL15663510	0.74	KDR (0.40)	KDRPDGFRAMETCYP3A4LMNA
	SCHEMBL2209534	0.74	MAPT (0.48)	KDRTDP1ALDH1A1LMNAMEN1
	SCHEMBL15663783	0.74	KDR (0.40)	KDRPDGFRAMETCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.