SCHEMBL22076665

SCHEMBL22076665

CC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.56
▸ NPY1R P25929 9/20 0.56
▸ NPY5R Q15761 8/20 0.56
▸ NPY2R P49146 5/20 0.56
▸ GRIA1 P42261 1/20 0.51
▸ OPRD1 P41143 2/20 0.48
▸ OPRM1 P35372 1/20 0.48
▸ OPRK1 P41145 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347869 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RGRIA1
SCHEMBL30688407 0.93 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL31348910 0.90 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL9326037 0.89 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29735960 0.87 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL6245466 0.87 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL29391773 0.87 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RGRIA1
SCHEMBL7204779 0.87 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL31019151 0.86 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9522231 0.86 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073359-A1 RADIOLABELED BIOMOLECULES AND THEIR USE UNIV DUKE (US) 2025-03-06 — — US disclosed
US-20200188541-A1 RADIOLABELED BIOMOLECULES AND THEIR USE DUKE UNIVERSITY 2020-06-18 — — US disclosed
CN-110709106-A Radiolabeled biomolecules and uses thereof 杜克大学 2020-01-17 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250073359-A1 RADIOLABELED BIOMOLECULES AND THEIR USE DDB1, FABP1, DBNL NPY4R 3111/4885NPY1R 3524/4885NPY5R 4308/4885
US-20200188541-A1 RADIOLABELED BIOMOLECULES AND THEIR USE DDB1, FABP1, DBNL NPY4R 3111/4885NPY1R 3524/4885NPY5R 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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