SCHEMBL9522231

N=C(N)NCCC[C@H](NC(=O)CNC(=O)CN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	12/20	0.51

▸	NPY5R	Q15761	9/20	0.51

▸	NPY1R	P25929	8/20	0.51

▸	NPY2R	P49146	6/20	0.51

▸	CHRND	Q07001	6/20	0.50

▸	CHRNA1	P02708	2/20	0.50

▸	CHRNG	P07510	2/20	0.50

▸	CHRNB1	P11230	2/20	0.50

▸	NPBWR1	P48145	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31019151	0.92	NPY4R (0.59)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL9523164	0.91	TFPI (0.54)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL15092950	0.91	NPY4R (0.54)	NPY4RNPY5RNPY1RNPY2RCHRND
SCHEMBL15092953	0.91	NPY4R (0.54)	NPY4RNPY5RNPY1RNPY2RCHRND
SCHEMBL29993069	0.91	NPY4R (0.53)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL13107806	0.91	NPY4R (0.53)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL30509261	0.91	NPY4R (0.53)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL29794248	0.90	NPY4R (0.56)	NPY4RNPY5RNPY1RNPY2RCHRND
SCHEMBL30516190	0.90	NPY4R (0.57)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL29590830	0.90	NPY4R (0.53)	NPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0527189-A1	NOVEL CC-1065 ANALOGS	PHARMACIA & UPJOHN COMPANY (US)	1993-02-17	—	—	EP	disclosed