Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938252 | 0.98 | HSD11B1 (0.41) | HSD11B1BTKADH1CADH1AASGR1 | |
| SCHEMBL24622292 | 0.86 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D | |
| SCHEMBL13943891 | 0.82 | HSD11B1 (0.45) | HSD11B1BTKASGR1RAB9AKDM4D | |
| SCHEMBL4803692 | 0.81 | HSD11B1 (0.40) | HSD11B1ASGR1KAT8KDM4D | |
| SCHEMBL4804112 | 0.81 | HSD11B1 (0.40) | HSD11B1ASGR1KAT8KDM4D | |
| Formic Acid SCHEMBL27813341 | 0.81 | HSD11B1 (0.42) | HSD11B1BTKADH1CADH1AASGR1 | |
| SCHEMBL4552317 | 0.81 | HSD11B1 (0.44) | HSD11B1BTKADH1CADH1AASGR1 | |
| SCHEMBL228179 | 0.81 | HSD11B1 (0.46) | HSD11B1BTKASGR1RAB9AKDM4D | |
| SCHEMBL2380370 | 0.78 | HSD11B1 (0.43) | HSD11B1BTKASGR1KAT8RAB9A | |
| SCHEMBL21541517 | 0.77 | HSD11B1 (0.42) | HSD11B1BTKASGR1KAT8KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115506-A1 | QUINOLINONE AND BENZOXAZINE DERIVATIVES AS MUSCARINIC M1 AND/OR M4 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-06-11 | — | — | WO | disclosed |