Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 18/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078759 | 0.90 | OGA (0.47) | OGASMN1; SMN2 | |
| SCHEMBL26374539 | 0.87 | OGA (0.52) | OGASMN1; SMN2 | |
| SCHEMBL22079275 | 0.85 | OGA (0.57) | OGASMN1; SMN2 | |
| SCHEMBL22079362 | 0.82 | OGA (0.66) | OGA | |
| SCHEMBL22079365 | 0.81 | OGA (0.52) | OGASMN1; SMN2 | |
| SCHEMBL22079703 | 0.81 | OGA (0.46) | OGASMN1; SMN2 | |
| SCHEMBL26374189 | 0.80 | OGA (0.45) | OGASMN1; SMN2 | |
| SCHEMBL27100375 | 0.78 | OGA (0.54) | OGASMN1; SMN2 | |
| SCHEMBL27022332 | 0.76 | OGA (0.57) | OGA | |
| SCHEMBL22079723 | 0.76 | OGA (0.64) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891146-B1 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL DERIVATIVES USEFUL AS O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2020117961-A1 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-06-11 | — | — | WO | disclosed |