SCHEMBL27100375

SCHEMBL27100375

CNc1ncc(CN2CCN(C(C)=O)CC2C)s1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 18/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22079362 0.90 OGA (0.66) OGA
SCHEMBL22078759 0.88 OGA (0.47) OGASMN1; SMN2
SCHEMBL22079270 0.82 OGA (0.46) OGASMN1; SMN2
SCHEMBL27100392 0.80 OGA (0.52) OGASMN1; SMN2
SCHEMBL22078760 0.78 OGA (0.51) OGASMN1; SMN2
SCHEMBL27022332 0.77 OGA (0.57) OGA
SCHEMBL22079723 0.77 OGA (0.64) OGA
SCHEMBL21370037 0.76 OGA (0.44) OGASMN1; SMN2
SCHEMBL21370045 0.75 ALDH1A1 (0.47) OGASMN1; SMN2
SCHEMBL27100348 0.75 OGA (0.71) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4327814-A2 MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS Biogen MA Inc. (US) 2024-02-28 — — EP disclosed
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