Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361875 | 0.85 | SLC1A3 (0.48) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL30572826 | 0.82 | CYP1A2 (0.49) | MAPTHTR2CADRA2ATDP1CYP1A2 | |
| SCHEMBL29068503 | 0.82 | CYP1A2 (0.49) | MAPTHTR2CADRA2ATDP1CYP1A2 | |
| SCHEMBL29812691 | 0.82 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL3165396 | 0.82 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL22079080 | 0.81 | MAPT (0.41) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL12117371 | 0.80 | CHEK2 (0.55) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL20034967 | 0.79 | CYP1A2 (0.54) | MAPTHTR2CPGRADRA2ATDP1 | |
| SCHEMBL29569917 | 0.76 | METAP1 (0.52) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL3129344 | 0.76 | METAP1 (0.52) | CHEK2ROS1MARK3LTKFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099922-A1 | INSECT NEUROPEPTIDE ANALOGUES | Solasta Bio Limited (GB) | 2023-06-08 | — | — | WO | disclosed |
| WO-2020115076-A2 | INSECT CONTROL AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2020-06-11 | — | — | WO | disclosed |