Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079201 | 0.81 | CHEK2 (0.44) | MAPTCHEK2ROS1MARK3LTK | |
| SCHEMBL29812691 | 0.78 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL3165396 | 0.78 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL12117371 | 0.75 | CHEK2 (0.55) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL27585673 | 0.75 | RAB9A (0.60) | MAPTHTR2CADRA2ARAB9ASLC1A3 | |
| SCHEMBL22079053 | 0.73 | RAB9A (0.55) | MAPTRAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3719955 | 0.73 | CYP2A6 (0.45) | MAPTADRA2ARAB9AADRA2BADRA2C | |
| SCHEMBL29569917 | 0.72 | METAP1 (0.52) | MAPTCHEK2ROS1MARK3LTK | |
| SCHEMBL3129344 | 0.72 | METAP1 (0.52) | MAPTCHEK2ROS1MARK3LTK | |
| SCHEMBL28360994 | 0.72 | METAP1 (0.52) | MAPTCHEK2ROS1MARK3LTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115076-A2 | INSECT CONTROL AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2020-06-11 | — | — | WO | disclosed |