Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 5/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581167 | 0.73 | DEGS1 (0.36) | — | |
| SCHEMBL22079313 | 0.73 | — | — | |
| SCHEMBL21744590 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL22079317 | 0.70 | — | — | |
| SCHEMBL22041735 | 0.70 | RET (0.59) | RET | |
| SCHEMBL22041731 | 0.70 | RET (0.59) | RET | |
| SCHEMBL30239250 | 0.70 | RET (0.59) | RET | |
| SCHEMBL22079316 | 0.65 | AKT1 (0.37) | — | |
| SCHEMBL22511243 | 0.61 | RET (0.60) | RET | |
| SCHEMBL22080069 | 0.61 | RET (0.60) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114474-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 苏州信诺维医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |