Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27052092 | 0.92 | FGFR4 (0.56) | FGFR4BTKAURKAMAPKAPK2 | |
| SCHEMBL29596500 | 0.85 | FGFR4 (0.59) | FGFR4BTKAURKAMAPKAPK2 | |
| SCHEMBL22079452 | 0.85 | FGFR4 (0.49) | FGFR4BTKAURKAMAPKAPK2 | |
| SCHEMBL21026922 | 0.79 | FGFR4 (0.45) | FGFR4BTK | |
| SCHEMBL27051966 | 0.79 | FGFR4 (0.49) | FGFR4AURKAMAPKAPK2 | |
| SCHEMBL22079449 | 0.78 | FGFR4 (0.50) | FGFR4AURKAMAPKAPK2 | |
| SCHEMBL22079833 | 0.78 | FGFR4 (0.44) | FGFR4BTKAURKAMAPKAPK2 | |
| SCHEMBL27052551 | 0.76 | FGFR4 (0.45) | FGFR4AURKAMAPKAPK2 | |
| SCHEMBL21000257 | 0.71 | FGFR4 (1.00) | FGFR4AURKAMAPKAPK2 | |
| SCHEMBL20113669 | 0.70 | FGFR4 (0.40) | FGFR4AURKAMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663285-B1 | FORMYLPYRIDINE DERIVATIVE HAVING FGFR4 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-01-24 | — | — | EP | disclosed |
| EP-3663285-A1 | FORMYLPYRIDINE DERIVATIVE HAVING FGFR4 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-06-10 | — | — | EP | disclosed |