Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554123 | 1.00 | NR1H2 (0.46) | NR1H2USP2SMN1; SMN2USP30RECQL | |
| SCHEMBL29239209 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL22078745 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL29017228 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL16633471 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL24404847 | 0.87 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL21193259 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL16633062 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL16633063 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT | |
| SCHEMBL29017236 | 0.87 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327814-A2 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2020117961-A1 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-06-11 | — | — | WO | disclosed |