Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078745 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL21193259 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL16633062 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL16633063 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL16633471 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL29017236 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL29239209 | 1.00 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL24404847 | 0.88 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL16646451 | 0.88 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2RECQLGPR119 | |
| SCHEMBL22079700 | 0.87 | NR1H2 (0.46) | NR1H2USP2SMN1; SMN2RECQLGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075514-A | Pharmacologically active heterocyclic substituted pyrazolo [1,5-a ] pyrimidine derivatives | 吉瑞工厂 | 2023-05-05 | — | — | CN | disclosed |