SCHEMBL22079925

SCHEMBL22079925

O=C(O)CCCCCCCCCCCCCCCOc1ccc(S(=O)(=O)Nc2ncc(C(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)c(C(F)(F)F)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ PKM P14618 1/20 0.38
▸ CNR2 P34972 7/20 0.37
▸ FABP1 P07148 2/20 0.37
▸ GAA P10253 2/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ EGLN1 Q9GZT9 1/20 0.35
▸ ITGB3 P05106 1/20 0.34
▸ ITGA2B P08514 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682000 0.92 SMN1; SMN2 (0.37) SMN1; SMN2PKMCNR2GAAHDAC1
SCHEMBL24257977 0.89 CNR2 (0.48) SMN1; SMN2PKMCNR2GAAEGLN1
SCHEMBL22080340 0.89 SMN1; SMN2 (0.42) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL22029352 0.85 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL24257865 0.85 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL22080449 0.85 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL24257868 0.85 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL24257978 0.85 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1
SCHEMBL31682074 0.83 SMN1; SMN2 (0.38) SMN1; SMN2PKMGAAHDAC1EGLN1
SCHEMBL24257864 0.82 SMN1; SMN2 (0.43) SMN1; SMN2PKMFABP1GAAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 — — EP disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 — — US disclosed
US-20200181223-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181223-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R SMN1; SMN2 1332/4885PKM 1743/4885CNR2 3357/4885
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R SMN1; SMN2 1332/4885PKM 1743/4885CNR2 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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