SCHEMBL22083044

SCHEMBL22083044

C=C(C)C(=O)Oc1ccc(-c2ccc(OC(=O)C(=C)COC)c(-c3ccc(-c4ccc(OC(=O)C(=C)CO)cc4)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.39
ELANE P08246 1/20 0.38
KMT2A Q03164 3/20 0.36
ATM Q13315 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.33
SYK P43405 3/20 0.32
ALOX5 P09917 2/20 0.32
SLC6A9 P48067 1/20 0.32
PTPN1 P18031 1/20 0.32
RARB P10826 3/20 0.32
RARG P13631 3/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
AURKB Q96GD4 1/20 0.31
INCENP Q9NQS7 1/20 0.31
RARA P10276 2/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22082376 1.00 BACE1 (0.39) BACE1ELANEKMT2AATMPTGDR2
SCHEMBL22083555 0.96 BACE1 (0.41) BACE1ELANEKMT2AATMPTGDR2
SCHEMBL22082388 0.95 BACE1 (0.39) BACE1KMT2APTGDR2SYKALOX5
SCHEMBL22083549 0.92 BACE1 (0.41) BACE1KMT2APTGDR2SYKALOX5
SCHEMBL22082379 0.89 THRB (0.37) BACE1KMT2APTGDR2ALOX5SLC6A9
SCHEMBL22459281 0.88 BACE1 (0.50) BACE1ELANEKMT2AATMPTGDR2
SCHEMBL22459791 0.88 BACE1 (0.50) BACE1ELANEKMT2AATMPTGDR2
SCHEMBL21422423 0.87 BACE1 (0.41) BACE1ELANEKMT2AATMLMNA
SCHEMBL22459374 0.87 BACE1 (0.41) BACE1ELANEKMT2AATMLMNA
SCHEMBL22561128 0.87 BACE1 (0.41) BACE1ELANEKMT2AATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116380-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC株式会社 2020-06-11 WO disclosed