SCHEMBL22084352

SCHEMBL22084352

CCC(=C(C)C)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL6982615 0.89 TDP1 (0.36) ALDH1A1TDP1
SCHEMBL25668913 0.79
SCHEMBL21500192 0.77
SCHEMBL7908207 0.75
SCHEMBL2976771 0.71 FFAR3 (0.35) ALDH1A1TDP1
SCHEMBL14776283 0.71 FFAR3 (0.35) ALDH1A1TDP1
SCHEMBL31268619 0.71 FAAH (0.36) ALDH1A1
SCHEMBL10528556 0.67
SCHEMBL14510245 0.67
SCHEMBL77659 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020114477-A1 COMPOUND ACTING AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND USES THEREOF 上海济煜医药科技有限公司 2020-06-11 WO disclosed