Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA3 | P07451 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA6 | P23280 | 4/20 | 0.34 |
| ▸ | CA5A | P35218 | 4/20 | 0.34 |
| ▸ | CA7 | P43166 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22086486 | 0.94 | CA2 (0.42) | CA2CA12CA1CA3CA4 | |
| SCHEMBL24754926 | 0.94 | KCNH2 (0.37) | CA2CA12CA1CA3CA4 | |
| SCHEMBL22086468 | 0.93 | KCNH2 (0.34) | CA2CA12CA1CA3CA4 | |
| SCHEMBL22085066 | 0.91 | KCNH2 (0.33) | CA2KCNH2HRH3KDM4EOPRM1 | |
| SCHEMBL22086481 | 0.87 | CA12 (0.38) | CA2CA12CA1CA3CA4 | |
| SCHEMBL24754700 | 0.86 | HRH3 (0.32) | KCNH2NT5EHRH3OPRM1HPGD | |
| SCHEMBL22086935 | 0.86 | RET (0.32) | CA2NT5EOPRM1HPGDRET | |
| SCHEMBL24754685 | 0.84 | CA2 (0.42) | CA2CA12CA1CA3CA4 | |
| SCHEMBL22086953 | 0.84 | KCNH2 (0.36) | KCNH2HRH3KDM4ETP53PKM | |
| SCHEMBL22085068 | 0.83 | KCNH2 (0.33) | KCNH2HRH3KDM4EOPRM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220404242-A1 | CELL-PERMEABLE FLUOROGENIC FLUOROPHORES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2022-12-22 | — | — | US | disclosed |
| WO-2020115286-A2 | CELL-PERMEABLE FLUOROGENIC FLUOROPHORES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2020-06-11 | — | — | WO | disclosed |