Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552631 | 1.00 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL292595 | 0.86 | PBRM1 (0.41) | PABPC1APOBEC3AAPOBEC3GALDH1A1PBRM1 | |
| SCHEMBL292594 | 0.86 | PBRM1 (0.41) | PABPC1APOBEC3AAPOBEC3GALDH1A1PBRM1 | |
| SCHEMBL11482206 | 0.85 | PTGS1 (0.49) | ALDH1A1CYP3A4TDP1KMT2AMEN1 | |
| SCHEMBL23489140 | 0.84 | PBRM1 (0.40) | PABPC1APOBEC3AAPOBEC3GALDH1A1PBRM1 | |
| SCHEMBL11645305 | 0.84 | PABPC1 (0.48) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL7522491 | 0.83 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL9608808 | 0.82 | PABPC1 (0.55) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL2294116 | 0.82 | PABPC1 (0.55) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL664962 | 0.82 | PABPC1 (0.55) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220118055-A1 | RELEASABLE GLP-1 CONJUGATES | FISH & RICHARDSON PC | 2022-04-21 | — | — | US | disclosed |
| EP-2348120-B1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2014-06-11 | — | — | EP | disclosed |
| EP-2348120-A1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2011-07-27 | — | — | EP | disclosed |
| US-20060205056-A1 | Enzymatic method of making ethyl 3-hydroxy-3-phenylpropionate and their esters | ENZYTECH, LTD. (KR) | 2006-09-14 | — | — | US | disclosed |
| WO-2004070049-A1 | THE ENZYMATIC METHOD OF MAKING ETHYL 3-HYDROXY-3-PHENYLPROPIONATE AND THEIR ESTERS | ENZYTECH, LTD. (KR) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118055-A1 | RELEASABLE GLP-1 CONJUGATES | GLP1R, GIPR, IAPP | PABPC1 2779/4885APOBEC3A 3370/4885APOBEC3G 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.