Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912130 | 1.00 | KRAS (0.36) | KRAS | |
| SCHEMBL21912768 | 0.82 | — | — | |
| SCHEMBL21896256 | 0.79 | — | — | |
| SCHEMBL19637242 | 0.78 | KRAS (0.55) | KRAS | |
| SCHEMBL22087714 | 0.78 | KRAS (0.47) | KRAS | |
| SCHEMBL25021032 | 0.77 | — | — | |
| SCHEMBL25020775 | 0.71 | — | — | |
| SCHEMBL22725375 | 0.71 | — | — | |
| SCHEMBL21912169 | 0.71 | — | — | |
| SCHEMBL25021700 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118066-A1 | COMBINATION THERAPIES | Mirati Therapeutics, Inc. (US) | 2020-06-11 | — | — | WO | disclosed |