Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22087557 | 0.90 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22087551 | 0.90 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21637028 | 0.88 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL18963691 | 0.87 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22990581 | 0.84 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL1697216 | 0.84 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21393208 | 0.84 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21392956 | 0.84 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL3484940 | 0.84 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22087964 | 0.84 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117739-A1 | PROCESS FOR THE PREPARATION OF A CYCLIC DINUCLEOTIDE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-11 | — | — | WO | disclosed |